Medicine has a very distinct and highly specialized language. It is necessary for any student wishing to pursue a successful career in the medical field to acquire comprehension in this system of communication, including Allied Healthcare professionals.
Организатор
eDX
Medicine has a very distinct and highly specialized language. It is necessary for any student wishing to pursue a successful career in the medical field to acquire comprehension in this system of communication, including Allied Healthcare professionals. Learners will receive thorough instruction in developing fluency with medical terms. Medical vocabulary will be taught with specific emphasis on root (or stem words), prefixes, suffixes and abbreviations. By the end of this course learners will be expected to have a basic comprehension of medical terms and be able to communicate accurately to their peers in the field.
Terms associated with anatomy, physiology, pathology and diagnostic tests of different systems are discussed but no previous knowledge of these topics is necessary.
1. Medical revolutions in Biology
2. Biological applications in forensics, history, and agriculture.
3. The diversity of life
4. An overview of evolution and a comparison of prokaryotic and eukaryotic cells
5. The fundamental principles and intellectual framework of biology
1. Framework, Buchner, and Fractionating life
2. Molecular composition of cells
3. Covalent bonds
4. Non-covalent bonds
5. Lipids and phospholipids: creating boundaries
6. High energy molecules: ATP and carbohydrates
1. Amazing proteins: primary structure
2. Meet the amino acids
3. Secondary structure
4. Tertiary and quaternary structure
1. Design a channel protein
2. Enzymes and biochemical reactions
3. What do enzymes do?
4. How do enzymes work?
5. Influenza virus - tricks of a burglar
1. The energetics of pathways
2. Logical tricks of pathways
3. Glycolysis: a pathway to break down sugar
4. Regulation of pathways
5. Cellular respiration and fermentation
1. Background: Who was Mendel? Why Peas?
2. Mendel’s Experiments: controls and crosses
3. Definitions
4. Multiple traits: Mendel’s second law
5. Cytology
6. The chromosomal theory of inheritance
1. Meiosis
2. Fruit flies and linkage
3. Linkage Maps
4. Linkage Mapping
5. Sex chromosomes and sex linkage
1. X-linked recessive inheritance
2. Autosomal dominant inheritance
3. Autosomal recessive inheritance
4. Real human genetics
5. Garrod and inborn errors of metabolism
0. Garrod, Beadle, Tatum and the link between genetics and biochemistry
1. Yeast as a model organism
2. How to use genetics to study biochemistry: A mutant hunt
3. Tricks of a mutant hunt
4. Characterizing mutants: test of dominance
5. Characterizing mutants: complementation test
6. Characterizing mutants: epistasis test
1. The Transforming principle
2. Structure of DNA: nucleotides and base-pairing
3. Bacterial viruses
4. DNA structure, the race
1. Meselson and Stahl
2. Details of DNA replication
3. Additional details of DNA replication: topography and other enzymes
4. Additional details of DNA replication: fidelity
5. Kornberg’s enzyme
1. RNA
2. Transcription: making RNA copy of DNA
3. Translation: making a polypeptide from RNA
4. Peering back in time
1. Replication in different organisms
2. Transcription in different organisms
3. Translation in different organisms
1. β-galactosidase in E. coli
2. Lac operon, lactose regulation
3. Lac operon, glucose regulation
4. Hormone receptors in mammals
5. β-globin gene structure.
6. β-globin mutations
7. The β-globin region
0. Overview
1. Cutting and pasting molecules of DNA
2. Vectors
3. Transformation of host cells
4. Selection and creating a library
0. Review/Overview
1. Tricks for cloning
2. Different cloning vectors and source DNA
3. Finding your gene by complementation
4. Finding your gene by protein expression
1. Gel electrophoresis
2. DNA sequencing, the concept
3. DNA sequencing, implementation
4. Polymerase Chain Reaction (PCR)
0. Recombinant DNA review
1. Finding your gene: human Mendelian diseases
2. Finding markers across the genome for positional cloning
3. The Human Genome Project, genome assembly and analysis
4. Improvements since the Human Genome project
5. Improvements in DNA sequencing
1. Tour of the genome: the genomic landscape
2. Evolutionary comparison
3. Evolutionary comparison as a tool for biomedical research
4. DNA polymorphisms within humans
1. DNA polymorphism in medicine: Mendelian disease
2. DNA polymorphisms: polygenic disease
3. RNA variation
4. Protein localization on the genome
1. Adding and subtracting genes
2. RNA interference
3. Modern genome editing: TALEN proteins and CRSPR
1. Heart disease
2. Cholesterol
3. Lipoprotein particles
4. Connections to heart disease
5. Genetics of cholesterol levels
6. Rational therapy for FH heterozygotes
7. Modern strategies: PCSK9 and HDL
1. Cancer
2. Regulation of cell growth: growth factors and receptors
3. Regulation of cell growth: Ras
4. Regulation of cell growth: Ras signaling
5. Mutations that cause cancer
6. Anti-cancer therapy
1. DNA and law
2. Other forensic technologies
3. Gene patenting